Silicon Valley's Digital Apothecary

On Digital Apothecaries and Massive Open Online Interventions: A brief history

Hosted by Palo Alto University's
Institute for International Internet
Interventions for Health (i4Health)


Healthy Mood



Ánimo - Sharing Strategies to Maintain a Healthy Mood (In Spanish)

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Ánimo! is a research study where you will view and rate several short videos that describe strategies that might be helpful in changing what people think and do that leads to negative moods and relationship problems. We invite you to participate!


PATbot - Chatbot to Provide Guidance & Support for Parents of Children with Behavioral Problems

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PAT is designed to provide general guidance and support for parents of children with behavioral problems, based on various evidence-based parenting programs.


Wellbeing Tools for Children and Adolescents


COVID-19 Project

Wellbeing Tools for Children and Adolescents (In English and Spanish)

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This anonymous research study invites parents, caregivers, teachers, healthcare professionals, young adults, and the general public, to view and evaluate the usefulness of a series of short videos developed by the United States National Academies of Sciences, Engineering, and Medicine to help children and adolescents cope with feelings of stress, anxiety, and depression during COVID-19 and beyond. We want to share these strategies with as many people as possible and would like to obtain evaluations of the videos with adults who care for children, or young adults, whether or not they have children. We invite you to participate.


COVID-19 Research Project: What to think and do (In English, Spanish, and Chinese)

Recruitment for this study is now closed »

The COVID-19 pandemic has caused millions to stay at home or severely restrict their activities. This major disruption increases the risk for depression and anxiety. When outside forces reduce our ability to control our lives, it is important to focus on those things we CAN control. This study is creating an inventory of thoughts and activities that people all over the world have rated in terms of helpfulness in remaining emotionally healthy. By crowdsourcing this information and sharing it widely, we hope to help prevent serious depression and anxiety across the globe.


Interventions to Prevent Depression in New Mothers

Mothers and Babies Online Course (In English and Spanish)

Participate in this Course »

The Mothers and Babies Course is an online program that teaches skills to manage changes in how you feel. Designed for pregnant women, new mothers, and those who want to support them.


BabyText Study (In English and Spanish)

Recruitment for this study is now closed »

The BabyText Program is a research study that uses text messaging to teach skills based on the Mothers and Babies Course to manage changes in how you feel before and after pregnancy. Pregnant women and new mothers who are over 18 years and who reside in the U.S. may be eligible to join.

For more information visit:


Intervention to Manage Depression


Mood Screener


Link to this Study »

BetterBET (Better Behaviors, Emotions, and Thoughts) is an automated, interactive internet intervention ( to help individuals manage and overcome their symptoms of depression. BetterBET is based on cognitive-behavioral therapy, which is one of the most effective psychotherapies for improving mood. In each of BetterBET’s eight lessons, you will learn several specific, practical ways to improve your mood.


Free Mood and Depression Screener

Link to the Mood Screener »

If you think that you might be depressed, want to find out more about your mood, or that you might be at risk for depression, take the mood/depresion screener and get automatic detailed feedback. This mood screener is an automated website and is available in five languages; English, Spanish, Russian, Chinese, and Arabic.

Supported by the Internet World Helath Research Center (IWHRC) at University of California San Francisco/San Francisco General Hospital


Stop Smoking Resources



Kick It California

English »

Spanish »

Review stop smoking recourses provided by the state of California.


Preventing Depression During COVID-19 (in English and Spanish)

Link to recorded webinar in Spanish »

Link to recorded webinar in English »

Staying emotionally healthy is difficult in challenging times and the Covid-19 pandemic is no exception. This webinar will discuss psychological methods of treating depression that can be helpful in preventing symptoms of depression. Specifically, he will share cognitive-behavioral strategies – that is, how to use thoughts and activities to remain emotionally healthy.